Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø

XClose

Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Therapeutic Innovation Networks

Home
Menu

Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø BioFoundry Advanced Synthetic Biology Processes Facility

Operated within Charles Bell House research laboratories, the facility offers nucleic acid synthesis and molecular cloning services to Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø scientists.

Introducing the Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø BioFoundry, a state-of-the-art resource for advanced synthetic biology processes at Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø. Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø staff can now utilise the facility by submitting anÌý.Ìý

Operated within Charles Bell House research laboratories, the facility offers nucleic acid synthesis and molecular cloning services to Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø scientists. Our primary goal is to bring these typically outsourced technologies in-house, providing researchers with convenient access to cutting-edge capabilities.

Powering our operations is the newly installed BioXp platform, an automated system that enables efficient DNA, mRNA, and peptide synthesis. This technology offers the below services as standard:

  • De novoÌýsynthesis of DNA fragments up to 3 kb.
  • De novoÌýsynthesis of DNA fragments up to 7 kb with direct cloning into plasmid.
  • De novoÌýmRNA synthesis up to 1.8 kb (clean-cap, unmodified, or pseudouridine).
  • In vitroÌýDNA plasmid amplification.
  • In vitroÌýmRNA synthesis up to 10 kb from starter plasmids.

The facility's potential applications in research and teaching are diverse. There are further advanced processes that can be offered on a case-by-case basis. Please enquire to about these to discuss your project with a specialist:

  • Cas9 guide RNA cloning.
  • Custom TALEN synthesis and cloning.
  • De novoÌýassembly of large (up to 24kb) transgenes.
  • Synthesis of scanning libraries up to 3 kb.
  • Assembly of promoter libraries for preclinical testing.

BioXp Machine
Ìý
BioXp Machine

View Ìý(Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø log-in required).ÌýPayments will be made via Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø InterDepartmental Transfer (IDT).

Ìý

Watch the video: Ìý(Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø log-in required)

For enquiries, please contact Dr John Counsell (j.counsell@ucl.ac.uk)