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Profiles of Current PhD Students

Ibrahim Aldobiyan

NAME: Ibrahim Aldobiyan

EMAIL: ibrahim.aldobiyan.17@ucl.ac.uk

ACADEMIC BIOGRAPHY:

鈥⑻�听听 Bachelor of Science (BSc) in Biochemistry, University of Leeds (2012-2015), Final Research Project: 鈥�Defining the structure of the icosahedral capsid of Cowpea mosaic virus (CPMV) using Cryo-EM, using two different image processing software. Introduced to a number of computational programs: SPIDER, RELION and UCSF Chimera鈥�

鈥⑻�听听 Master of Science (MSc) in Drug Design, University College London (2017-2018), Final Research Project: 鈥淐haracterising the biochemical activities and structures of 伪₁-Antitrypsin mutants in presence of a polymerisation inhibitor鈥�

鈥⑻�听听 PhD, University College London (Sept 2018 鈥� Sept 2022), Research project: 鈥淭he "...". Funded by King Saud University (KSU) through the Royal Embassy of Saudi Arabia Cultural Bureau in the UK & Ireland (UKSACB)

PROFESSIONAL BIOGRAPHY:

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PhD AIM:

The aim of my PhD is to utilise various biochemical, cellular biology听and biophysical techniques with an emphasis on cryo-electron microscopy, in order听to elucidate in molecular detail the polymerisation mechanism antitrypsin undergoes to form pathological polymers

RESEARCH INTERESTS:

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PUBLICATIONS/CONFERENCES:

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Kamila Kamuda

NAME: Kamila Kamuda

EMAIL: k.kamuda@ucl.ac.uk

ACADEMIC BIOGRAPHY:

鈥⑻�听听听 Academic Profession degree in Chemical and Biotechnical Science, Business Academy Aarhus (Sept 2011 鈥� Jan 2014), Final Research Project: 鈥淭he role of Wnt-5a signalling on the newborn neurons migration in the Rostral Migratory Stream鈥�

鈥⑻�听听听 Bachelor of Science (BSc) in Molecular Biology and Chemistry, Roskilde University (Sept 2014 鈥� June 2016), Final Research Project "The interaction of the N and C terminal regions of the Bloom syndrome helicase with the Dissolvasome complex"

鈥⑻�听听听 Master of Science (MSc) in Human Biology, University of Copenhagen (Sept 2016 鈥� Aug 2018), Final Research Project: 鈥淐haracterization of the interaction between human CCT chaperonin and its substrates鈥�

鈥⑻�听听听 PhD, University College London (Sept 2018 鈥� Sept 2022), Research project: 鈥淭he cellular consequences of polymer accumulation in alpha-1-antitrypsin deficiency elucidated in molecular detail鈥�. PhD is funded by Wellcome Trust as part of the ISMB 4-year Interdisciplinary PhD programme in Structural, Chemical and Computational Biology

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PROFESSIONAL BIOGRAPHY:

鈥⑻�听听听 Internship (Feb 2013 鈥� Jan 2014), Research Assistant (Feb 2014 鈥� Jun 2014) in Fluorescent Tissue Profiling group led by Dr Jan Mulder, Science for Life Laboratory, Department of Neuroscience, Karolinska Institutet

鈥⑻�听听听 Laboratory assistant (Nov 2014 鈥� Oct 2015), Laboratory technician (Nov 2015 鈥� Sept 2018) in Structural Molecular Biology group led by Prof. Guillermo Montoya, NNF Center for Protein Research, University of Copenhagen

鈥⑻�听听听 Demonstrator at Birkbeck College (Autumn term 2019/2020) for Practical Skills for Biosciences (BSc) and Molecular Microbiology (MSc) courses

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PhD AIM:

The aim of my PhD is to investigate the effect of the polymerogenic mutations of 伪₁-antitrypsin at the cellular and molecular level. I am using various approaches from cellular and molecular biology to understand the pathogenic consequence of the polymerization occurring in cells.

RESEARCH INTERESTS:

I am very interested in applying integrative structural biology to understand protein function at the molecular level and therefore I use a combination of techniques to answer my key research questions. The primary technique I use is electron microscopy, supported by protein crystallography, NMR and various biochemical assays.

Additionally, I am interested in developing computer programming skills and their implementation in my research, e.g. for data processing purposes.

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PUBLICATIONS/CONFERENCES:

Wang D., Kamuda K., Montoya G. and Mesa P. The TRiC/CCT Chaperonin and Its Role in Uncontrolled Proliferation. Adv Exp Med Biol. 1243:21-40 (2020)

FENS meeting 2014 Milan, G017 poster (co-author), 鈥淭owards an antibody-based protein atlas of the mouse brain鈥�

Instruct ERIC 2019 Alcal谩 de Henares, Madrid, poster presentation, 鈥淪tructural effects of synthetic peptide incorporation in 伪₁-antitrypsin 鈥�

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Marina Nick

NAME: Marina Nick

EMAIL: marina.nick.18@ucl.ac.uk

ACADEMIC BIOGRAPHY:

鈥⑻�听听听 Bachelor of Science (BSc)

鈥⑻�听听听 Master of Science (MSc)

鈥⑻�听听听 PhD, University College London (Sept 2018 鈥� Sept 2022), Research project: 鈥淭he "...". Funded by .....

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PhD AIM:

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RESEARCH INTERESTS:

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PUBLICATIONS/CONFERENCES:

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Sarah Lowen

NAME: Sarah Lowen

EMAIL: s.lowen@ucl.ac.uk

ACADEMIC BIOGRAPHY:

鈥⑻�听听听 Bachelor of Science (BSc)

鈥⑻�听听听 Master of Science (MSc)

鈥⑻�听听听 PhD, University College London (Sept 2018 鈥� Sept 2022), Research project: 鈥淭he "...". Funded by .....

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PhD AIM:

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RESEARCH INTERESTS:

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PUBLICATIONS/CONFERENCES:

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Sarah Vickers

NAME: Sarah Vickers

EMAIL: s.vickers@ucl.ac.uk

ACADEMIC BIOGRAPHY:

鈥⑻�听听听 Bachelor of Science (BSc)

鈥⑻�听听听 Master of Science (MSc)

鈥⑻�听听听 PhD, University College London (Sept 2018 鈥� Sept 2022), Research project: 鈥淭he "...". Funded by .....

PROFESSIONAL BIOGRAPHY:

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PhD AIM:

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RESEARCH INTERESTS:

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PUBLICATIONS/CONFERENCES:

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FORMER STUDENTS

FORMER PhD STUDENTS

Name	Email	Thesis
Sarah Faull	s.faull@ucl.ac.uk	听
Emma Elliston	e.elliston@alumni.ucl.ac.uk	听
Anwen Brown	a.brown@ucl.ac.uk	听
Alistair Jagger	a.jagger@ucl.ac.uk	听

FORMER MASTERS STUDENTS

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