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Dr Richard Horton FRCP FMedSci ,听editor-in-chief of The Lancet,听introduced Professor Carol Brayne CBE, Professor of Public Health Medicine and Co-Director of Cambridge Public Health Interdisciplinary Centre at the University of Cambridge.听

Professor Brayne听has pioneered the study of dementia in population.听Since the mid-80s Carol鈥檚 principal area of research has been longitudinal studies of the health of older people, with a focus on the brain, from a public health perspective. This included pioneering work bringing biology to populations including the creation of brain banks for medical research from population studies.

She also leads听The Public Health of Ageing Research Unit, an involved team of specialised dementia researchers whose work includes specific risk reduction trials, studies of ageing and technology, age-friendly cities, plus the impact of ageing and dementia in the populations of low and middle-income countries.听A fellow of the听Academy of Medical Sciences, Carol was听awarded a听CBE听for services to public health medicine in the Queen鈥檚 2017 Honours.

Professor Brayne's lecture "鈥淭he relevance of social and commercial determinants for neurological health: The听Lancet Neurology听lecture鈥� gave听a public health perspective on influences on manifestation of neurological disorders.听

Carol began by thanking her co-authors Sebastian Walsh and Richard Merrick. She put their听work in the context of celebrating 20 years of Lancet Neurology, directions of neurological science over that period, and the importance of epidemiology. She highlighted听the Global Burden of Neurological Diseases, including changing patterns in stroke, epilepsy and meningitis, and the听WHO intersectional global action plan's goals for epilepsy and other neurological diseases.

Carol then discussed societal trends, e.g. increasing ageing and inequalities, as well as climate change, and their significance in shaping neurological disease. She gave听example case studies, demonstrating the听impact of inequalities on risk and protective factors, supporting the听key messages of frameworks for social and commercial determinants of health and听tiers of prevention, and the impact of听individual behaviour vs policy change. She showed how these determinants cluster and听influence our lifecourse and pathways to neurological disease, e.g.听stroke, and provided a Framework for brain health optimisation.听Carol highlighted the听challenges for neurological science in reflecting societal experiences, and meeting Sustainable Development Goals.

Carol concluded by looking听to the future, and actions we can take as leaders, mentors and influencers,听in clinical practice, teaching and research, to advocate听and raise听awareness.听

The introduction and closing remarks were given by听Professor Gipi Schiavo, IoN Deputy Director,听who celebrated听Carol's lecture in the context听of recent听developments in neurological science and public health.

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Image:听Professor Gipi Schiavo, Professor Alan Thompson, Professor Carol Brayne,听Dr Richard Horton, and Elena Becker-Barroso