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Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Cancer Domain Symposium 2019

The Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Cancer Domain Symposium, entitled 'Rethinking Cancer', took place on Monday 13 May 2019.

Over 430 people attended the inaugural Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Cancer Domain Symposium. Speakers and attendees representingÌýa wide range of disciplines across Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø and partner organisations, assembledÌýfor the first time at such a large scale to consider challenges and opportunities in cancer research, prevention and treatment, from biological, clinical, technical, economic and societal perspectives. Ìý

Video recordings of the presentations and panel discussions can be found below. They are a great resource, so if you missed the event, or even if you were there, please take a look for a unique insight into some of the most pressing questions and cutting edge research being deployed to beat cancer research and the innovative multi-disciplinary approaches that are being deployed across Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø and beyond.Ìý

A full programme from the day can be found here.

Opening remarks and Session One:ÌýCancer evolution: can we beat Nature?

Opening remarks and Professor Charles Swanton Ìý(Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Cancer Institute and The Francis Crick Institute) - Cancer evolution, immune evasion and metastatic progression - insights from TRACERx

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Dr Duncan Greig (Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Department of Genetics, Evolution and Environment) - Microbes as models for cancer evolution

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Professor David Gems (Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Institute of Healthy Ageing, GEE) - Learning about cancer from an organism that doesn’t get cancer

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Professor Tariq Enver (Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Cancer Institute) - Origins and evolution of childhood Leukaemia

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Panel discussion with all speakers and moderatorsÌý

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(can be downloaded)Ìý
Session Two - Early Careers Network session

Dr Marina Parry and Dr Maria Secrier (Cancer Early Career Network Co-chairs) - Introduction toÌýCancer Early Career Network

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Emma Beecham (Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Great Ormond Street Institute of Child Health) - Exploration of the concept ‘quality of life’ in consultations of children with a high risk brain tumour over the course of the illness

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Monica Koo (Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Institute of Epidemiology and Health Care) - Common cancer symptoms at presentation and associated stage at diagnosis

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Alexandra Lubin (Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Cancer Institute) - Targeted therapeutics for AML: automated high-throughput drug screening in zebrafish

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Lydia Neary-Zajiczek (Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø TouchLab) - Using image registration, segmentation and region growing to generate whole sample stiffness maps of cancerous and healthy tissue

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Christopher Steele (Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Cancer Institute) - Molecular fingerprints of copy number alterations in human cancer

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Yin Wu (Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Cancer Institute) - Cancer immunology: putting the pedal to the metal

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Session Three – Cancer detection: the earlier the better?

Professor Caroline Moore (Urology, Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø and Ïã¸ÛÁùºÏ²ÊÖÐÌØÍøH) - Prostate cancer detection - benefits and harms of early detection

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Dr Nora Pashayan (Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Institute of Epidemiology and Health Care) - Risk stratification for population based screening: Optimising the benefit-harm tradeoffs

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Professor Sam Janes (Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Respiratory Medicine) - Detecting lung cancer earlier: Crawling to the SUMMIT

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Panel discussion with speakers and moderators

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(can be downloaded)Ìý
Session Four – The cancer treatment revolution and how we afford it

Professor Marcel Levi (Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø and Chief Executive, Ïã¸ÛÁùºÏ²ÊÖÐÌØÍøH) - New cancer drugs in the 21st century: an acceptable bang for your buck?

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Dr Claire Roddie (Haematology, Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø) - Cellular Immunotherapy for Cancer: better targets, better targeting

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Professor Gary Royle (Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Department of Medical Physics and Biomedical Engineering) - Targeting tumours with protons
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Keynote address: Professor Mariana Mazzucato (Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Institute for Innovation and Public Purpose) - Bringing public value and purpose to the centre of health innovation: a mission oriented approach

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Panel discussion with speakers and moderators
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(can be downloaded)Ìý
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Closing remakrs - Professor Mark Emberton
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