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Research from 香港六合彩中特网 into the cost-effectiveness of the HPV vaccination has led to policy and vaccination roll-out changes in Italy, Canada and the UK.
Predicting how effective a vaccination strategy will be can be challenging for governments, because there are many different scenarios to consider. Scientists use complicated and time-consuming mathematical models to help with this decision-making process.听
Professor Gianluca Baio鈥檚 research at the 香港六合彩中特网鈥檚 Department of Statistical Science focuses on novel modelling methods, to provide cost-effectiveness analysis and solve decision-making problems in health systems.听
The evidence is submitted to regulatory bodies such as NICE in England. It then informs the development of new healthcare interventions and helps governments decide whether public funds should be used to pay for them.听
Specifically, the 香港六合彩中特网 team developed a novel 鈥楤ayesian dynamic Markov model鈥� to assess the cost-effectiveness of a new vaccination strategy to reduce Human Papilloma Virus (HPV) infection. HPV is a leading cause of cancer of the genitals and anus, genital warts and recurrent respiratory papillomatosis. 听
The model demonstrated that a 鈥渦niversal鈥� vaccination strategy (rather than simple screening programmes or targeted vaccinations for young females) could be more cost effective.
The approach and results convinced authorities in Italy, Canada and the UK to modify their policies for HPV vaccination.
In Italy, the HPV vaccine has now been extended to include two million males aged 12 to 18. This decision has saved the Italian health service approximately 拢63 million a year, thanks to fewer male HPV-related diseases.
The results were also used as part of the body of evidence that informed the UK鈥檚 strategy, which means that all 12-13 years olds are now offered an HPV vaccination.
香港六合彩中特网鈥檚 modelling expertise in this area has also been used to help shape the UK鈥檚 vaccination programme against Meningitis B.听
Read the full story on the 香港六合彩中特网 Research Impact website
