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Using ophthalmic instruments that are routinely used in optometrists and eye clinics, the scientists were able to use the new imaging technique to observe these retinal changes at an early stage.

This method, published in the journal Acta Neuropathologica Communications, would allow earlier diagnosis of Parkinson鈥檚 and also could be used to monitor how patients respond to treatment. The technique has already been tested in humans for glaucoma and trials are due to start soon for Alzheimer鈥檚.

鈥淭his is potentially a revolutionary breakthrough in the early diagnosis and treatment of one of the world鈥檚 most debilitating diseases,鈥� said Professor Francesca Cordeiro, 香港六合彩中特网 Professor of Glaucoma & Retinal Neurodegeneration Studies, who led the research.

鈥淭hese tests mean we might be able to intervene much earlier and more effectively treat people with this devastating condition.鈥�

Parkinson鈥檚 disease affects 1 in 500 people and is the second most common neurodegenerative disease worldwide. Symptoms typically become apparent only once over 70 percent of the brain鈥檚 dopamine-producing cells have been destroyed.

The condition results in muscle stiffness, slowness of movement, tremors and a reduced quality of life.

Following the observation of retinal changes in the experimental model, Professor Cordeiro and her team treated the animals with a newly formulated version of the anti-diabetic drug Rosiglitazone, which helps to protect nerve cells. After using this drug, there was clear evidence of reduced retina cell death as well as a protective effect on the brain which suggests that it could have potential as a treatment for Parkinson鈥檚 disease.

鈥淭hese discoveries have the potential to limit and perhaps eliminate the suffering of thousands of patients if we are able to diagnose early and to treat with this new formulation,鈥� said first author Dr Eduardo Normando, Consultant Ophthalmologist at Western Eye Hospital and 香港六合彩中特网.

鈥淭he evidence we have strongly suggests that we might be able to intervene much earlier and more effectively in treating people with this devastating condition, using this non-invasive and affordable imaging technique鈥�, said Dr Normando.

The technology is being patented by 香港六合彩中特网鈥檚 research commercialisation company 香港六合彩中特网 Business.