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Anas Sherif has been awarded his PhD for his thesis entitled听The development of a novel method to assess the adhesive interaction of adult stem cells with biomaterial substrates using AFM.

The project involved research which was part of an ongoing theme in the Biomaterials and Tissue Engineering Department at the EDI.

In his work, Dr Sherif used highly-localised probe functionalised with 鈥渓ive-cells鈥� to investigate the mode of adhesion of these cells onto implants surfaces such as titanium.

Using this pioneering approach, he provided new knowledge and understanding on the mode of interactions between cell and host, which will undoubtedly lead to more work in implants鈥� surfaces development.

Dr Sherif鈥檚 Supervisors were听 and

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Elena Calciolari has also been awarded her PhD for her thesis Intramembranous bone healing and the effect of osteoporosis on the jawbones.

This looked at the effect of osteoporosis on the jawbones and investigated听at a molecular and histological level the process of intramembranous osseous formation.

Principle supervisor,听, said听鈥淒r Calciolari's project was the first project听combining听histological features and proteomic analyses to shade light on the complex mechanism of bone formation.

鈥淭hrough her pioneering work, Dr Calciolari was able to show differently听expressed proteins in healthy and osteoporotic conditions,听which could be听targeted by future studies to enhance bone regeneration in the presence of reduce bone density.

鈥淭he results of the thesis also showed how different titanium surfaces can promote bone formation by听regulating signalling pathways听involved in osseous formation.

鈥淐ongratulations to Dr Calciolari for her hard work and听excellent听outcome鈥�

Dr Calciolari鈥檚 Secondary Supervisor was