Centre for Cardiovascular Disease Imaging

The focus of our group is to understand the heart and use this to improve the lives of patients. We develop new tests and measurement techniques linking technical development to human variation (health, rare and common diseases) from idea to global delivery. Examples include LGE, T1, T2, ECV mapping, perfusion mapping, AI analytics, new metrology/QC frameworks, rapid CMR and CMR for pacemakers. We are one of the most innovative global research groups in cardiology. We aim to change how people think about the heart and accelerate delivery across boundaries (clinical disciplines, basic science, global healthcare).

Lead

Professor James Moon

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Senior academic team/collaborators:
1. Dr Peter Kellman, NIH (visiting professor 香港六合彩中特网 and Barts)
2. Dr Charlotte Manisty June 2014: Senior Lecturer in Heart failure and CMR 香港六合彩中特网 and Barts
3. Prof Marianna Fontana, Deputy director, National Amyloid Centre and Director, CMR
4. Dr Guy Lloyd December 2014: Echo lead (former president BSE, BSE secretary)
5. Dr Christos Bourantas (invasive imaging) 香港六合彩中特网 and Barts
6. Dr Leon Menezes, lead in nuclear cardiology across 香港六合彩中特网H and Barts听
7. Dr Gaby Captur, senior lecturer in rare diseases and health/aging, 香港六合彩中特网, Barts and Royal Free听
8. Dr Thomas Treibel, senior lecturer, BHF Intermediate, 香港六合彩中特网 and Barts
9. Dr Rhodri Davies, senior lecturer, machine learning for medical imaging, 香港六合彩中特网 and Barts
10. Dr Luis Lopes, senior lecturer, genetic cardiomyopathy 香港六合彩中特网 and Barts听
11. Dr Viviana Maestrini, senior lecturer, La Sapienza, Rome
12. Dr Rebecca Kozor, senior lecturer, director of CMR, University of Sydney, Australia
13. Dr Camilla Torlasco, senior lecturer, Universit脿 degli Studi di Milano-Bicocca, Director of CMR, Milan

In collaboration with Dr Francesca Pugliese (CT) and Prof Steffen Petersen (Queen Mary University)

Infrastructure听(香港六合彩中特网H BRC, including BHC, CMIC, Royal Free, Great Ormond Street).

Barts Heart Centre: the largest cardiac centre in Europe including the largest global CMR centre, Europes largest cardiac CT services; UKs largest echo service.
Chenies Mews Imaging Centre: part of the 香港六合彩中特网 phenotyping centre, including 13 research clinic rooms, DEXA, 3x CPEX, and space for 20 researchers (Profs A Hughes, N Chatu
Royal Free, Great Ormond Street: 3x Aera

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Hardware: CMR: 3x Aera, 2x Prisma, all upgraded with 32-64 core Linux boxes and cloud reconstruction. CT: 1x Force. Echo: 19 machines, 5 sites. Nuclear: 4 sites inc PET-CT.
Activity (pa): 18,000 CMRs, 4500 cardiac CTs, 60,000 echos, 2500 nuclear cardiac scans.
Software: 3 CVI servers, ~30 workstations; Syngo.via x 2 networks, Hermes, Tomtec, GE image vault, REDCap running >250 studies.听 5.7Tb image Corelab. SFTP file exchange server

National/International Collaborations

: The leading longitudinal mild disease COVID-19 cohort (~10 university collaboration).
AS700 鈥� a 7 centre UK CMR study in severe AS
Fabrys400 a 6 centre CMR study (Birmingham, London x 3, Sydney, Brisbane)
T1MES program - a 79 centre CMR T1 mapping phantom standardisation project
REDCap for UK cardiovascular research. Currently 250 research projects
Marathon platform: 250 subjects pre and post training for first marathon.
香港六合彩中特网:NIH partnership for new sequence validation by Peter Kellman
Perfusion mapping group: 13 centre collaboration 听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听
Rapid CMR: projects in 8 countries.听 , links to 27 other countries. 听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听
Heartome1000: Advanced imaging and 1000 cardiac biopsies to basic science (Utrecht, Pamplona, ICH)听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听
Artificial Intelligence: 4 key centres: increase cardiac imaging precision
MRI for pacemakers: aiming for 50,000 UK scans pa, saving 500 lives. www.mrimypacemaker.com
Advanced HCM phenotyping: DTI, ECGi, perfusion mapping for HCM (4 centres)

Current grants

听Around 14 active grants

2022 FS/CRTF/21/24269 鈥淒eep structural phenotype of hypertrophic cardiomyopathy; from mutation to听hypertrophy鈥� George Joy听拢209,391.99
2021听 ~8 COVID grants eg MRC UKRI 拢725K, NIHR rolling COVID 拢800K all as co-applicant
2020听 Barts Charity: COVIDsortium: 拢1.46m. Chief investigator, plus extension funding
2020听 SBRI phase 2 OpenCare commercialisation of AI for cardiac analysis 拢700K co-applicant听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听
2019 听Multiple AI grants (BHF x 3; SBRI phase 1)
2019听 Dr Luis Lopes, Senior Lecturer, MRC CARP, Profs Elliott/Moon
2019听 Dr Tom Treibel, Senior Lecturer, BHF Intermediate, Profs Moon/Hughes
2019听 Dr Rhodri Davies, Senior Lecturer, CAP-AI/BHF accelerator, Prof Moon/Hughes/Alexander
2018听听Arrhythmia in Fabry Disease: Role of Implantable Loop Recorders.鈥� 拢800K co-I
2018听听 Dr Kush Patel, the role of the myocardium in TAVI patients (Edwards) ~60K
2018听听 The pathophysiology of revascularisation of the poor LV: 拢150K, Barts Charity
2017听听 Rebecca Hughes: The extended spectrum of apical HCM, 拢250K BHF听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听听
2016听听The new cardiac phenotyping centre, 香港六合彩中特网 (2 magnets - 拢1.39million contribution 香港六合彩中特网H charity)