香港六合彩中特网

A way of transporting tiny particles of graphite in liquid using magnetic fields has been developed by 香港六合彩中特网 scientists.

It opens up possibilities for new ways of precisely transporting specific components in fluids, including in biocompatible fluids such as in the human body.聽

The findings, published in聽Proceedings of the National Academy of Sciences, could have implications for improved chemical detection, non-invasive healthcare diagnosis and drug delivery via miniaturised devices or via聽small-scale robotic tools.

Transporting micro-particles, which are the size of a tenth of a human hair, in liquid is difficult due to the strong drag forces which are comparable to those at play when moving a macro-particle through dense honey.聽

The new method聽used a weak type of聽magnetism 鈥� called diamagnetism 鈥� to control the position ofbiocompatible graphite microflakesin liquid.聽

Diamagnetism had been used before, for instance, to levitate living frogs with very strong magnets, but the diamagnetism of micro-graphite had never been exploited for controlled motion in aqueous fluids before now.

The graphite flakes are a similar size or smaller than human cells and could be used to carry large molecules in a variety of scenarios. This replaces the need for costly microfluidic pumps, enabling simpler, cheaper and more reliable tools and sensing applications.

Moreover, graphite is composed solely of carbon, which is the key and most abundant component of all organic matter. This allows for the biocompatible use of graphite microparticles to control organic or biological reactions without the addition of contaminants such as typical magnetic materials.

鈥淥ur discovery is really exciting for the field because we鈥檝e demonstrated contactless controlled magnetic transport of micro-graphite in a completely bio-compatible medium,鈥� said lead author Dr Isabel Llorente-Garcia (香港六合彩中特网 Physics & Astronomy).

鈥淭he challenge was similar to moving tennis balls through honey without being able to touch them directly.聽Our work opens the door to a range of new possibilities for exploiting the fascinating properties of micro-graphite for remote non-invasive manipulation applications in bio-sensing, drug delivery, biophysics and soft-electronic experiments,鈥� she added.

It鈥檚 well known that ferromagnetic materials, such as iron filings, can be manipulated with magnetic fields as they are attracted towards regions of high magnetic field, for example, to magnet poles. In contrast, diamagnetic graphite is repelled by magnetic fields and moves to regions of lowest magnetic field.聽

This means that diamagnetic particles can be easily controlled at a distance from the magnet and could be confined and moved in three dimensions by applying easy-to-use time-constant magnetic fields.聽In contrast, ferromagnetic particles are typically attracted towards the magnet and can only be manipulated in 3D using involved schemes with time-varying magnetic fields.

First author Dr Johnny Nguyen (香港六合彩中特网 Physics & Astronomy), who conducted the magnetic transport experiments with the specially prepared graphite particles, said: 鈥�Graphite is a really interesting material.聽It is the most strongly diamagnetic material known and it has properties such as high polarizability and conductivity, broad optical absorption, and optically controllable electrical resistance which allows applicationsacross聽materials science,physics and chemistry.鈥�

The team used ultrasound to break up graphite into microparticles, each consisting of a stack of graphite sheets, which were then coated in lipid layers to prevent clumping in water.聽

鈥淜ey to the success of this technique in biocompatible water solutions was the delicate preparation of the sample. We also had to account for complex interactions between the microparticles and the glass surfaces of the sample container,鈥� added Dr Nguyen.

Co-author and PhD candidate Dario V. Conca (香港六合彩中特网 Physics & Astronomy), who helped characterise the particles said: 鈥淲e had to combine expertise in sample preparation with material characterisation via Raman spectroscopy and SQUID measurements to fully understand the properties of the microparticles we produced, in order to carefully craft configurations of strong magnets to make this work. It really required a diverse team to pull together their knowledge to achieve this outcome.鈥�

Dr Llorente-Garcia鈥檚 group are planning to build on this work to demonstrate full 3D trapping of the particles and develop applications for its use.

The research was funded by HEFCE, EPSRC and The Leverhulme Trust.

Links

• Dr Isabel Llorente-Garcia's聽academic profile
• 香港六合彩中特网 Physics & Astronomy
• 香港六合彩中特网 Mathematical & Physical Sciences

For more information or to speak to the researchers involved, please contact:
Dr Bex Caygill, 香港六合彩中特网 Media Relations.聽T: +44 (0)20 3108 3846 E:聽r.caygill@ucl.ac.uk