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A 10-year review of TB notifications and mortality trends using a joint point analysis in Zambia - a high TB burden country. (2022) Lungu, P., C. Kasapo, R. Mihova, R. Chimzizi, L. Sikazwe, I. Banda, L. A. Mucheleng'anga, P. Chanda-Kapata, N. Kapata, A. Zumla and P. Mwaba. Int J Infect Dis 124 Suppl 1: S30-S40

A 24-Week, all-oral regimen for rifampin-resistant tuberculosis. (2022) Nyang'wa, B. T., C. Berry, E. Kazounis, I. Motta, N. Parpieva, Z. Tigay, V. Solodovnikova, I. Liverko, R. Moodliar, M. Dodd, N. Ngubane, M. Rassool, T. D. McHugh, M. Spigelman, D. A. J. Moore, K. Ritmeijer, P. du Cros, K. Fielding and T.-P. S. Collaborators. N Engl J Med 387(25): 2331-2343

Accuracy of Xpert Ultra for the diagnosis of paediatric tuberculosis in a low TB burden country: a prospective multicentre study. (2022) Aguilera-Alonso, D., G. Solis-Garcia, A. Noguera-Julian, J. Gonzalez-Martin, A. Roman Cobena, F. Baquero-Artigao, C. Toro Rueda, P. Rodriguez-Molino, I. Bloise Sanchez, T. Vallmanya, A. Bernet-Sanchez, L. Minguell Domingo, A. Rubio, J. Saavedra-Lozano, M. J. Ruiz-Serrano, D. Blazquez-Gamero, P. Lopez-Roa, D. Gomez-Pastrana, M. D. Lopez Prieto, E. M. Lopez Medina, A. Gil-Brusola, A. Martin Nalda, A. Soriano-Arandes, T. Tortola, L. Falcon-Neyra, V. Gonzalez Galan, M. Tebruegge and B. Santiago-Garcia. Thorax 77(10): 1023-1029

Ancient and recent differences in the intrinsic susceptibility of Mycobacterium tuberculosis complex to pretomanid. (2022) Bateson, A., J. Ortiz Canseco, T. D. McHugh, A. A. Witney, S. Feuerriegel, M. Merker, T. A. Kohl, C. Utpatel, S. Niemann, S. Andres, K. Kranzer, F. P. Maurer, A. Ghodousi, E. Borroni, D. M. Cirillo, M. Wijkander, J. C. Toro, R. Groenheit, J. Werngren, D. Machado, M. Viveiros, R. M. Warren, F. Sirgel, A. Dippenaar, C. U. Koser, E. Sun and J. Timm. J Antimicrob Chemother 77(6): 1685-1693

Ancient DNA confirmation of lepromatous leprosy in a skeleton with concurrent osteosarcoma, excavated from the leprosarium of St. Mary Magdalen in Winchester, Hants.ÌýUK. (2022) Cole, G., G. M. Taylor, G. R. Stewart and H. Dawson-Hobbis. Eur J Clin Microbiol Infect Dis

Applying learning health systems thinking in codeveloping integrated tuberculosis interventions in the contexts of COVID-19. (2022) van Rensburg, A. J., I. Petersen, A. Awotiwon, M. O. Bachmann, R. Curran, J. Murdoch, C. J. Ras and L. Fairall. BMJ Glob Health 7(10)

Are mRNA based transcriptomic signatures ready for diagnosing tuberculosis in the clinic? - A review of evidence and the technological landscape. (2022) Hamada, Y., A. Penn-Nicholson, S. Krishnan, D. M. Cirillo, A. Matteelli, R. Wyss, C. M. Denkinger, M. X. Rangaka, M. Ruhwald and S. G. Schumacher. EBioMedicine 82: 104174

Bacillus Calmette-Guerin skin reaction predicts enhanced mycobacteria-specific T-cell responses in infants: A post hoc analysis of a randomized controlled trial. (2022) Pittet, L. F., N. Fritschi, M. Tebruegge, B. Dutta, S. Donath, N. L. Messina, D. Casalaz, W. A. Hanekom, W. J. Britton, R. Robins-Browne, N. Curtis and N. Ritz. Am J Respir Crit Care Med 205(7): 830-841

Bacterial growth dynamics and pharmacokinetic-pharmacodynamic relationships of rifampicin and bedaquiline in BALB/c mice. (2022) Muliaditan, M. and O. Della Pasqua. Br J Pharmacol 179(6): 1251-1263

Bedaquiline adherence measured by electronic dose monitoring predicts clinical outcomes in the treatment of patients with multidrug-resistant tuberculosis and HIV/AIDS. (2022) O'Donnell, M. R., N. Padayatchi, A. Wolf, J. Zelnick, A. Daftary, C. Orrell, C. Nimmo, M. Baldwin, R. Boodhram, B. Maharaj, K. R. Amico, K. Naidoo and G. Friedland. J Acquir Immune Defic Syndr 90(3): 325-332

Bedaquiline-pretomanid-linezolid regimens for drug-resistant tuberculosis. (2022) Conradie, F., T. R. Bagdasaryan, S. Borisov, P. Howell, L. Mikiashvili, N. Ngubane, A. Samoilova, S. Skornykova, E. Tudor, E. Variava, P. Yablonskiy, D. Everitt, G. H. Wills, E. Sun, M. Olugbosi, E. Egizi, M. Li, A. Holsta, J. Timm, A. Bateson, A. M. Crook, S. M. Fabiane, R. Hunt, T. D. McHugh, C. D. Tweed, S. Foraida, C. M. Mendel, M. Spigelman and T. ZeNix Trial. N Engl J Med 387(9): 810-823

Bilateral optic neuritis as a first presentation of lymph node tuberculosis. (2022) Keshavan, A., L. McAnena, J. F. Acheson, H. Booth, G. T. Plant and Z. Khaleeli. Pract Neurol 22(1): 51-54

Blue skies research is essential for ending the tuberculosis pandemic and advancing a personalized medicine approach for holistic management of respiratory tract infections. (2022) Ntoumi, F., E. Petersen, P. Mwaba, E. Aklillu, S. Mfinanga, D. Yeboah-Manu, M. Maeurer and A. Zumla. Int J Infect Dis 124 Suppl 1: S69-S74

Bolaamphiphile analogues of 12-bis-THA Cl(2) Are potent antimicrobial therapeutics with distinct mechanisms of action against bacterial, mycobacterial, and fungal pathogens. (2022) Di Blasio, S., M. Clarke, C. K. Hind, M. Asai, L. Laurence, A. Benvenuti, M. Hassan, D. Semenya, D. K. Man, V. Horrocks, G. Manzo, S. Van Der Lith, C. Lam, E. Gentile, C. Annette, J. Bosse, Y. Li, B. Panaretou, P. R. Langford, B. D. Robertson, J. K. W. Lam, J. M. Sutton, M. McArthur and A. J. Mason. mSphere: e0050822

C2-linked alkynyl poly-ethylene glycol (PEG) adenosine conjugates as water-soluble adenosine receptor agonists. (2022) Ferguson, L., N. S. Madieh, A. Vaideanu, A. Schatzlein, J. Festa, H. Singh, G. Wells, S. Bhakta and F. Brucoli. Chem Biol Drug Des

The cascade of care for latent tuberculosis infection in congregate settings: A national cohort analysis, Korea, 2017-2018. (2022) Min, J., H. W. Kim, H. R. Stagg, M. X. Rangaka, M. Lipman, I. Abubakar, Y. Lee, J. P. Myong, H. Jeong, S. Bae, A. Y. Shin, J. Y. Kang, S. S. Lee, J. S. Park, H. W. Yim and J. S. Kim. Front Med (Lausanne) 9: 927579

Case studies to illustrate good practice in the management of non-tuberculous mycobacterial pulmonary disease. (2022) Tiberi, S., M. C. Lipman and A. Floto. Respir Med Case Rep 38: 101668

Cell-level spatio-temporal model for a Bacillus Calmette-Guerin-based immunotherapy treatment protocol of superficial bladder cancer. (2022) Lazebnik, T. Cells 11(15)

Challenges in defining the functional, non-coding, expressed genome of members of the Mycobacterium tuberculosis complex. (2022) Stiens, J., K. B. Arnvig, S. L. Kendall and I. Nobeli. Mol Microbiol 117(1): 20-31

Clinical standards for drug-susceptible pulmonary TB. (2022) Akkerman, O. W., R. Duarte, S. Tiberi, H. S. Schaaf, C. Lange, J. W. C. Alffenaar, J. Denholm, A. C. C. Carvalho, M. S. Bolhuis, S. Borisov, J. Bruchfeld, A. M. Cabibbe, J. A. Caminero, I. Carvalho, J. Chakaya, R. Centis, M. P. Dalcomo, D. A. L, M. Dedicoat, K. Dheda, K. E. Dooley, J. Furin, J. M. Garcia-Garcia, N. A. H. van Hest, B. C. de Jong, X. Kurhasani, A. G. Martson, S. Mpagama, M. M. Torrico, E. Nunes, C. W. M. Ong, D. J. Palmero, R. Ruslami, A. M. I. Saktiawati, C. Semuto, D. R. Silva, R. Singla, I. Solovic, S. Srivastava, J. E. M. de Steenwinkel, A. Story, M. G. G. Sturkenboom, M. Tadolini, Z. F. Udwadia, A. R. Verhage, J. P. Zellweger and G. B. Migliori. Int J Tuberc Lung Dis 26(7): 592-604

Clinical standards for the diagnosis, treatment and prevention of TB infection. (2022) Migliori, G. B., S. J. Wu, A. Matteelli, D. Zenner, D. Goletti, S. Ahmedov, S. Al-Abri, D. M. Allen, M. E. Balcells, A. L. Garcia-Basteiro, E. Cambau, R. E. Chaisson, C. B. E. Chee, M. P. Dalcolmo, J. T. Denholm, C. Erkens, S. Esposito, P. Farnia, J. S. Friedland, S. Graham, Y. Hamada, A. D. Harries, A. W. Kay, A. Kritski, S. Manga, B. J. Marais, D. Menzies, D. Ng, L. Petrone, A. Rendon, D. R. Silva, H. S. Schaaf, A. Skrahina, G. Sotgiu, G. Thwaites, S. Tiberi, N. Tukvadze, J. P. Zellweger, D. A. L, R. Centis and C. W. M. Ong. Int J Tuberc Lung Dis 26(3): 190-205

Clinical utility of C-reactive protein-based triage for presumptive pulmonary tuberculosis in South African adults. (2023) Calderwood, C. J., B. W. Reeve, T. Mann, Z. Palmer, G. Nyawo, H. Mishra, G. Ndlangalavu, I. Abubakar, M. Noursadeghi, G. Theron and R. K. Gupta. J Infect 86(1): 24-32

Cognitive impairment in tuberculous meningitis. (2022) Davis, A. G., A. J. Dreyer, C. Albertyn, M. Maxebengula, C. Stek, S. Wasserman, S. Marais, K. Bateman, M. Solms, J. Joska, R. J. Wilkinson and S. Nightingale. Clin Infect Dis

Comparison of 8 weeks standard treatment (rifampicin plus clarithromycin) vs. 4 weeks standard plus amoxicillin/clavulanate treatment [RC8 vs. RCA4] to shorten Buruli ulcer disease therapy (the BLMs4BU trial): study protocol for a randomized controlled multi-centre trial in Benin. (2022) Johnson, R. C., E. Saez-Lopez, E. S. Anagonou, G. G. Kpoton, A. G. Ayelo, R. S. Gnimavo, F. Z. Mignanwande, J. G. Houezo, G. E. Sopoh, J. Addo, L. Orford, G. Vlasakakis, N. Biswas, F. Calderon, O. Della Pasqua, A. Gine-March, Z. Herrador, A. Mendoza-Losana, G. Diez, I. Cruz and S. Ramon-Garcia. Trials 23(1): 559

A comparison of vitamin D and cathelicidin (LL-37) levels between patients with active TB and their healthy contacts in a high HIV prevalence setting: a prospective descriptive study. (2022) Lungu, P. S., W. Kilembe, S. Lakhi, T. Sukwa, E. Njelesani, A. I. Zumla and P. Mwaba. Trans R Soc Trop Med Hyg 116(4): 336-343

The contribution of late HIV diagnosis on the occurrence of HIV-associated tuberculosis. (2022) Girardi, E., Y. Caro-Vega, A. Cozzi-Lepri, J. Musaazi, G. Carriquiry, B. Castelnuovo, A. Gori, Y. C. Manabe, J. E. Gotuzzo, A. D'Arminio Monforte, B. Crabtree-Ramirez and C. Mussini. AIDS 36(14): 2005-2013

The contribution of late HIV diagnosis on the occurrence of HIV-associated tuberculosis: a 5-year estimate using real-world data. (2022) Girardi, E., Y. Caro-Vega, A. Cozzi-Lepri, J. Musaazi, G. Carriquiry, B. Castelnuovo, A. Gori, Y. C. Manabe, J. E. Gotuzzo, A. D'Arminio Monforte, B. Crabtree-Ramirez and C. Mussini. AIDS

Cost-effectiveness of a medication event monitoring system for tuberculosis management in Morocco. (2022) Yang, J., H. Y. Kim, S. Park, I. Sentissi, N. Green, B. K. Oh, Y. Kim, K. H. Oh, E. Paek, Y. J. Park, I. H. Oh and S. H. Lee. PLoS One 17(4): e0267292

Country differences and determinants of yield in programmatic migrant TB screening in four European countries. (2022) Menezes, D., D. Zenner, R. Aldridge, S. R. Anderson, G. de Vries, C. Erkens, V. Marchese, A. Matteeli, M. Muzyamba, J. Nederby-Ohd, J. van Rest, I. Spruijt, J. Were, K. Lonnroth, I. Abubakar and F. Cobelens. Int J Tuberc Lung Dis 26(10): 942-948

Culture-free enumeration of Mycobacterium tuberculosis in mouse tissues using the molecular bacterial load assay for preclinical drug development. (2022) Evangelopoulos, D., C. M. Shoen, I. Honeyborne, S. Clark, A. Williams, G. V. Mukamolova, M. H. Cynamon and T. D. McHugh. Microorganisms 10(2)

Defining discriminatory antibody fingerprints in active and latent tuberculosis. (2022) Nziza, N., D. Cizmeci, L. Davies, E. B. Irvine, W. Jung, B. A. Fenderson, M. de Kock, W. A. Hanekom, K. Franken, C. L. Day, T. H. M. Ottenhoff and G. Alter. Front Immunol 13: 856906

Delamanid-containing regimens and multidrug-resistant tuberculosis: A systematic review and meta-analysis. (2022) Nasiri, M. J., M. Zangiabadian, E. Arabpour, S. Amini, F. Khalili, R. Centis, L. D'Ambrosio, J. T. Denholm, H. S. Schaaf, M. van den Boom, X. Kurhasani, M. P. Dalcolmo, S. Al-Abri, J. Chakaya, J. W. Alffenaar, O. Akkerman, D. R. Silva, M. Munoz-Torrico, B. Seaworth, E. Pontali, L. Saderi, S. Tiberi, A. Zumla, G. B. Migliori and G. Sotgiu. Int J Infect Dis 124 Suppl 1(Suppl 1): S90-S103

Design and protocol for a cluster randomised trial of enhanced diagnostics for tuberculosis screening among people living with HIV in hospital in Malawi (CASTLE study). (2022) Burke, R. M., S. Nyirenda, H. H. Twabi, M. Nliwasa, E. Joekes, N. Walker, R. Nyirenda, A. Gupta-Wright, K. Fielding, P. MacPherson and E. L. Corbett. PLoS One 17(1): e0261877

Diagnostic accuracy of WHO screening criteria to guide lateral-flow lipoarabinomannan testing among HIV-positive inpatients: A systematic review and individual participant data meta-analysis. (2022) Dhana, A., Y. Hamada, A. P. Kengne, A. D. Kerkhoff, T. Broger, C. M. Denkinger, M. X. Rangaka, A. Gupta-Wright, K. Fielding, R. Wood, H. Huerga, S. C. M. Rucker, S. Bjerrum, I. S. Johansen, S. S. Thit, M. M. Kyi, J. Hanson, D. A. Barr, G. Meintjes and G. Maartens. J Infect 85(1): 40-48

The diagnostic performance of novel skin-based in-vivo tests for tuberculosis infection compared with purified protein derivative tuberculin skin tests and blood-based in vitro interferon-gamma release assays: a systematic review and meta-analysis. (2022) Krutikov, M., L. Faust, V. Nikolayevskyy, Y. Hamada, R. K. Gupta, D. Cirillo, A. Mateelli, A. Korobitsyn, C. M. Denkinger and M. X. Rangaka. Lancet Infect Dis 22(2): 250-264

Dolutegravir twice-daily dosing in children with HIV-associated tuberculosis: a pharmacokinetic and safety study within the open-label, multicentre, randomised, non-inferiority ODYSSEY trial. (2022) Turkova, A., H. Waalewijn, M. K. Chan, P. D. J. Bollen, M. F. Bwakura-Dangarembizi, A. R. Kekitiinwa, M. F. Cotton, A. Lugemwa, E. Variava, G. M. Ahimbisibwe, U. Srirompotong, V. Mumbiro, P. Amuge, P. Zuidewind, S. Ali, C. M. Kityo, M. Archary, R. A. Ferrand, A. Violari, D. M. Gibb, D. M. Burger, D. Ford, A. Colbers and O. T. Team. Lancet HIV 9(9): e627-e637

Drug resistant TB - latest developments in epidemiology, diagnostics and management. (2022) Tiberi, S., N. Utjesanovic, J. Galvin, R. Centis, L. D'Ambrosio, M. van den Boom, A. Zumla and G. B. Migliori. Int J Infect Dis 124 Suppl 1: S20-S25

Dual latent tuberculosis screening with tuberculin skin tests and QuantiFERON-TB assays before TNF-alpha inhibitor initiation in children in Spain. (2023) Calzada-Hernandez, J., J. Anton, J. Martin de Carpi, B. Lopez-Montesinos, I. Calvo, E. Donat, E. Nunez, J. Blasco Alonso, M. J. Mellado, F. Baquero-Artigao, R. Leis, A. M. Vegas-Alvarez, M. Medrano San Ildefonso, M. D. C. Pinedo-Gago, F. J. Eizaguirre, A. Tagarro, M. Camacho-Lovillo, B. Perez-Gorricho, C. Gavilan-Martin, S. Guillen, B. Sevilla-Perez, L. Pena-Quintana, P. Mesa-Del-Castillo, C. Fortuny, M. Tebruegge and A. Noguera-Julian. Eur J Pediatr 182(1): 307-317

ECCO topical review on clinicopathological spectrum and differential diagnosis of inflammatory bowel disease. (2022) Feakins, R., J. Torres, P. Borralho-Nunes, J. Burisch, T. Curdia Goncalves, L. De Ridder, A. Driessen, T. Lobaton, L. Menchen, A. Mookhoek, N. Noor, M. Svrcek, V. Villanacci, N. Zidar and M. Tripathi. J Crohns Colitis 16(3): 343-368

ECG monitoring in STREAM Stage 1: can we identify those at increased risk of QT prolongation? (2022) Hughes, G., H. Bern, C. Y. Chiang, R. L. Goodall, A. J. Nunn, I. D. Rusen and S. K. Meredith. Int J Tuberc Lung Dis 26(11): 1065-1070

Economic evaluation of shortened, bedaquiline-containing treatment regimens for rifampicin-resistant tuberculosis (STREAM stage 2): A within-trial analysis of a randomised controlled trial. (2023) Rosu, L., J. J. Madan, E. M. Tomeny, M. Muniyandi, J. Nidoi, M. Girma, V. Vilc, P. Bindroo, R. Dhandhukiya, A. K. Bayissa, D. Meressa, G. Narendran, R. Solanki, A. K. Bhatnagar, E. Tudor, B. Kirenga, S. K. Meredith, A. J. Nunn, G. Bronson, I. D. Rusen, S. B. Squire, E. Worrall and S. S. H. E. E. Collaborators. Lancet Glob Health 11(2): e265-e277

Effect of dysglycemia on urinary lipid mediator profiles in persons with pulmonary tuberculosis. (2022) Arriaga, M. B., F. Karim, A. T. L. Queiroz, M. Araujo-Pereira, B. Barreto-Duarte, C. Sales, M. S. Moosa, M. Mazibuko, G. L. Milne, F. Maruri, C. H. Serezani, J. R. Koethe, M. C. Figueiredo, A. L. Kritski, M. Cordeiro-Santos, V. C. Rolla, T. R. Sterling, A. Leslie and B. B. Andrade. Front Immunol 13: 919802

Elevated IP-10 at the protein and gene level associates with pulmonary TB. (2022) Fisher, K. L., D. Moodley, K. Rajkumar-Bhugeloo, O. O. Baiyegunhi, F. Karim, H. Ndlovu, T. Ndung'u and M. J. Marakalala. Front Cell Infect Microbiol 12: 908144

Elevated plasma matrix metalloproteinase 8 associates with sputum culture positivity in pulmonary tuberculosis. (2022) Walker, N. F., F. Karim, M. Y. S. Moosa, S. Moodley, M. Mazibuko, K. Khan, T. R. Sterling, Y. F. van der Heijden, A. D. Grant, P. T. Elkington, A. Pym and A. Leslie. J Infect Dis 226(5): 928-932

Emergence of phenotypic and genotypic antimicrobial resistance in Mycobacterium tuberculosis. (2022) Kloprogge, F., J. Ortiz Canseco, L. Phee, Z. Sadouki, K. Kipper, A. A. Witney, N. Stoker and T. D. McHugh. Sci Rep 12(1): 21429

Ending the tuberculosis syndemic: is COVID-19 the (in)convenient scapegoat for poor progress? (2022) Rangaka, M. X., Y. Hamada and I. Abubakar. Lancet Respir Med 10(6): 529-531

End-point definition and trial design to advance tuberculosis vaccine development. (2022) Garcia-Basteiro, A. L., R. G. White, D. Tait, A. C. Schmidt, M. X. Rangaka, M. Quaife, E. Nemes, R. Mogg, P. C. Hill, R. C. Harris, W. A. Hanekom, M. Frick, A. Fiore-Gartland, T. Evans, A. F. Dagnew, G. Churchyard, F. Cobelens, M. A. Behr and M. Hatherill. Eur Respir Rev 31(164)

Estimating annual risk of infection with Mycobacterium tuberculosis. (2022) Yates, T. A. and P. Y. Khan. Lancet Infect Dis 22(9): 1276-1277

Estimating the contribution of transmission in primary healthcare clinics to community-wide TB disease incidence, and the impact of infection prevention and control interventions, in KwaZulu-Natal, South Africa. (2022) McCreesh, N., A. S. Karat, I. Govender, K. Baisley, K. Diaconu, T. A. Yates, R. M. Houben, K. Kielmann, A. D. Grant and R. White. BMJ Glob Health 7(4)

Evaluating the effect of short-course rifapentine-based regimens with or without enhanced behaviour-targeted treatment support on adherence and completion of treatment for latent tuberculosis infection among adults in the UK (RID-TB: Treat): protocol for an open-label, multicentre, randomised controlled trial. (2022) Rangaka, M. X., Y. Hamada, T. Duong, H. Bern, J. Calvert, M. Francis, A. L. Clarke, A. Ghanouni, C. Layton, V. Hack, E. Owen-Powell, J. Surey, K. Sanders, H. L. Booth, A. Crook, C. Griffiths, R. Horne, H. Kunst, M. Lipman, M. Mandelbaum, P. J. White, D. Zenner and I. Abubakar. BMJ Open 12(9): e057717

Evaluation of host protein biomarkers by ELISA From whole lysed peripheral blood for development of diagnostic tests for active tuberculosis. (2022) Garlant, H. N., K. Ellappan, M. Hewitt, P. Perumal, S. Pekeleke, N. Wand, J. Southern, S. V. Kumar, H. Belgode, I. Abubakar, S. Sinha, S. Vasan, N. M. Joseph and K. E. Kempsell. Front Immunol 13: 854327

Evaluation of SARS-CoV-2 diagnostics and risk factors associated with SARS-CoV-2 infection in Zambia. (2022) Tembo, J., N. F. Egbe, K. Maluzi, K. Mulonga, M. Chilufya, N. Kapata, V. Mukonka, E. Simulundu, A. Zumla, S. Fwoloshi, L. Mulenga, S. R. Pallerla, T. P. Velavan and M. Bates. Int J Infect Dis 120: 150-157

Evaluation of two short standardised regimens for the treatment of rifampicin-resistant tuberculosis (STREAM stage 2): an open-label, multicentre, randomised, non-inferiority trial. (2022) Goodall, R. L., S. K. Meredith, A. J. Nunn, A. Bayissa, A. K. Bhatnagar, G. Bronson, C. Y. Chiang, F. Conradie, M. Gurumurthy, B. Kirenga, N. Kiria, D. Meressa, R. Moodliar, G. Narendran, N. Ngubane, M. Rassool, K. Sanders, R. Solanki, S. B. Squire, G. Torrea, B. Tsogt, E. Tudor, A. Van Deun, I. D. Rusen and S. s. collaborators. Lancet 400(10366): 1858-1868

Experimental autoimmune uveitis: An intraocular inflammatory mouse model. (2022) Bowers, C. E., V. L. Calder, J. Greenwood and M. Eskandarpour. J Vis Exp(179)

Failure or relapse predictors for the STREAM Stage 1 short regimen for RR-TB. (2022) Kokebu, D. M., S. Ahmed, R. Moodliar, C. Y. Chiang, G. Torrea, A. Van Deun, R. L. Goodall, I. D. Rusen, S. K. Meredith and A. J. Nunn. Int J Tuberc Lung Dis 26(8): 753-759

A feasibility study evaluating the uptake, effectiveness and acceptability of routine screening of pregnant migrants for latent tuberculosis infection in antenatal care: a research protocol. (2022) Rahman, A., S. Thangaratinam, A. Copas, D. Zenner, P. J. White, C. Griffiths, I. Abubakar, C. McCourt and H. Kunst. BMJ Open 12(4): e058734

Fluoroquinolone preventive therapy for children exposed to MDR-TB. (2022) Gureva, T., A. Turkova, E. Yablokova, P. Smirnova, O. Sveshnikova, O. Zolotaya, E. Nikishova, E. Heldal, S. Hinderaker, J. A. Seddon and A. Mariandyshev. Int J Tuberc Lung Dis 26(2): 171-173

Forgiveness is the attribute of the strong: Nonadherence and regimen-shortening in drug-sensitive TB. (2022) Stagg, H. R., J. A. Thompson, M. C. Lipman, D. J. Sloan, M. Flook, K. L. Fielding and T. B. D. R. Critical Path to. Am J Respir Crit Care Med

Genome-wide association with uncertainty in the genetic similarity matrix. (2022) Wang, S., S. Ge, B. Sobkowiak, L. Wang, L. Grandjean, C. Colijn and L. T. Elliott. J Comput Biol

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Tuberculosis drug discovery: challenges and new horizons. (2022) Fernandes, G. F. S., A. M. Thompson, D. Castagnolo, W. A. Denny and J. L. Dos Santos. J Med Chem 65(11): 7489-7531

Tuberculosis following two-dose SARS-CoV-2 vaccination with messenger RNA vaccine (BNT162b2) and inactivated virus vaccine (CoronaVac). (2022) Li, X., K. Peng, F. W. T. Cheng, D. C. L. Lam, C. L. Cheung, C. S. L. Chui, F. T. T. Lai, E. Y. F. Wan, C. K. H. Wong, T. Ma, S. H. H. Yum, E. W. Y. Chan, J. D. Huang, C. S. Lau, M. S. M. Ip and I. C. K. Wong. J Infect

Tuberculosis incidence in country of origin is a key determinant of the risk of active tuberculosis in people living with HIV: Data from a 30-year observational cohort study. (2022) White, H. A., H. Okhai, P. Kirwan, S. H. Rafeeq, H. Dillon, P. Hefford, M. J. Wiselka and M. Pareek. HIV Med 23(6): 650-660

Tuberculosis prevalence: beyond the tip of the iceberg. (2022) Houben, R., H. Esmail, F. Cobelens, C. M. L. Williams and A. K. Coussens. Lancet Respir Med 10(6): 537-539

Tuberculosis screening among ambulatory people living with HIV: a systematic review and individual participant data meta-analysis. (2022) Dhana, A., Y. Hamada, A. P. Kengne, A. D. Kerkhoff, M. X. Rangaka, T. Kredo, A. Baddeley, C. Miller, S. Singh, Y. Hanifa, A. D. Grant, K. Fielding, D. Affolabi, C. S. Merle, A. P. Wachinou, C. Yoon, A. Cattamanchi, C. J. Hoffmann, N. Martinson, E. T. Mbu, M. S. Sander, T. T. Balcha, S. Skogmar, B. W. P. Reeve, G. Theron, G. Ndlangalavu, S. Modi, J. Cavanaugh, S. Swindells, R. E. Chaisson, F. Ahmad Khan, A. A. Howard, R. Wood, S. S. Thit, M. M. Kyi, J. Hanson, P. K. Drain, A. E. Shapiro, T. Kufa, G. Churchyard, D. T. Nguyen, E. A. Graviss, S. Bjerrum, I. S. Johansen, J. K. Gersh, D. J. Horne, S. M. LaCourse, H. A. A. Al-Darraji, A. Kamarulzaman, R. R. Kempker, N. Tukvadze, D. A. Barr, G. Meintjes and G. Maartens. Lancet Infect Dis 22(4): 507-518 (21)00387-X

Tuberculosis screening among HIV-positive inpatients: a systematic review and individual participant data meta-analysis. (2022) Dhana, A., Y. Hamada, A. P. Kengne, A. D. Kerkhoff, M. X. Rangaka, T. Kredo, A. Baddeley, C. Miller, A. Gupta-Wright, K. Fielding, R. Wood, H. Huerga, S. C. M. Rucker, C. Heidebrecht, D. Wilson, S. Bjerrum, I. S. Johansen, S. S. Thit, M. M. Kyi, J. Hanson, D. A. Barr, G. Meintjes and G. Maartens. Lancet HIV 9(4): e233-e241

Tuberculosis surveillance in Romania among vulnerable risk groups between 2015 and 2017. (2022) Munteanu, I., N. Cioran, R. van Hest, I. Abubakar, A. Story, D. Chiotan, G. de Vries and B. Mahler. Ther Clin Risk Manag 18: 439-446

Tuberculosis, HIV/AIDS and malaria health services in sub-Saharan Africa - A situation analysis of the disruptions and impact of the COVID-19 pandemic. (2022) Chanda-Kapata, P., F. Ntoumi, N. Kapata, P. Lungu, L. A. Mucheleng'anga, J. Chakaya, J. Tembo, C. Himwaze, R. Ansumana, D. Asogun, S. Mfinanga, P. Nyasulu, P. Mwaba, D. Yeboah-Manu, A. Zumla and J. B. Nachega. Int J Infect Dis 124 Suppl 1: S41-S46

The two extremes of Hansen's disease-Different manifestations of leprosy and their biological consequences in an Avar Age (late 7th century CE) osteoarchaeological series of the Duna-Tisza Interfluve (Kiskundorozsma-Daruhalom-dulo II, Hungary). (2022) Spekker, O., B. Tihanyi, L. Kis, O. A. Varadi, H. D. Donoghue, D. E. Minnikin, C. Szalontai, T. Vida, G. Palfi, A. Marcsik and E. Molnar. PLoS One 17(6): e0265416

Understanding the tuberculosis granuloma: the matrix revolutions. (2022) Elkington, P., M. E. Polak, M. T. Reichmann and A. Leslie. Trends Mol Med 28(2): 143-154

An unusual case of tuberculous spondylodiscitis in a patient with multiple neck masses. (2022) Said, A., R. Balachandar and N. van Vucht. BJR Case Rep 8(3): 20210079

Urine tuberculosis diagnostics in patients with advanced HIV. (2022) Nel, J. and A. Gupta-Wright. AIDS 36(6): 897-898

Utility of esophageal ultrasound-guided biopsy of mediastinal lymph nodes in diagnosis of childhood tuberculosis. (2022) Cohen, J. M., M. Banks, O. M. Kon and S. Eisen. Pediatr Infect Dis J 41(5): e246-e248

Variation in initial health assessment of unaccompanied asylum-seeking children: a cross-sectional survey across England. (2022) Nezafat Maldonado, B., A. J. Armitage and B. Williams. BMJ Paediatr Open 6(1)

The war in Ukraine and potential consequences for the TB epidemic in Europe. (2022) Sotgiu, G., I. Solovic, D. Zenner, S. Tiberi, K. Manika, C. Celan, J. Chorostowska-Wynimko, A. Zumla and G. B. Migliori. Int J Tuberc Lung Dis 26(5): 470-471

The WHO Global Tuberculosis 2021 Report - Not so good news and turning the tide back to End TB. (2022) Chakaya, J., E. Petersen, R. Nantanda, B. N. Mungai, G. B. Migliori, F. Amanullah, P. Lungu, F. Ntoumi, N. Kumarasamy, M. Maeurer and A. Zumla. Int J Infect Dis 124 Suppl 1: S26-S29

Whole genome sequencing and prediction of antimicrobial susceptibilities in non-tuberculous mycobacteria. (2022) Solanki, P., M. Lipman, T. D. McHugh and G. Satta. Front Microbiol 13: 1044515

Why has the incidence of tuberculosis not reduced in London during the COVID-19 pandemic? (2022) Lewer, D., R. Mulchandani, A. Roche, C. Cosgrove and C. Anderson. Lancet Respir Med 10(3): 231-233

World TB Day 2022: Revamping and reshaping global TB control programs by advancing lessons learnt from the COVID-19 pandemic. (2022) Petersen, E., S. Al-Abri, J. Chakaya, D. Goletti, L. Parolina, C. Wejse, L. A. Mucheleng'anga, S. A. Khalili, D. Yeboah-Manu, P. Chanda-Kapata, M. J. Nasiri, P. S. Lungu, M. Maeurer, S. Tiberi, F. Ntoumi, G. Battista-Migliori and A. Zumla. Int J Infect Dis 124 Suppl 1: S1-S3

World Tuberculosis Day 2022: Aligning COVID-19 and tuberculosis innovations to save lives and to end tuberculosis. (2022) Ntoumi, F., J. B. Nachega, E. Aklillu, J. Chakaya, I. Felker, F. Amanullah, D. Yeboah-Manu, K. G. Castro and A. Zumla. Lancet Infect Dis 22(4): 442-444

Other Outputs

Report of the technical consultation on innovative clinical trial designs for evaluating new TB preventive treatments.ÌýVirtual meeting,Ìý15-17ÌýSeptemberÌý2021 (published 2022).Ìý World Health Organization (WHO) Global Tuberculosis Programme, in collaboration withÌýUniversity College London and other partners, convened a virtual technical consultationÌýfrom 15 to 17 September 2021 that focused on innovative clinical trial designs that could beÌýused for evaluating new tuberculosis (TB) preventive treatments (TPTs). The objectives ofÌýthe meeting were to identify and summarize challenges in designing future TPT trials and toÌýexplore innovative designs that could facilitate advances in biomedical TB preventiveÌýinterventions and would complement similar developments in other fields relevant to TBÌýprevention.ÌýDiscussions were organized in four main sessions:ÌýSession 1: Models of delivery;ÌýSession 2: Estimating the benefits and harms of TPT;ÌýSession 3: Trial design and analytical approaches;ÌýSession 4: Trial populations.ÌýYohhei Hamada and Molebogeng (Lele) Rangaka, both from the Institute forÌýGlobal Health and the Medical Research Council (MRC) Clinical Trials Unit at University CollegeÌýLondon (Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø), drafted the concept note and helped organize the meeting. Elena Pallari andÌýGenevieve Wills, both also from the MRC Clinical Trials Unit at Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø, served as meetingÌýrapporteurs. Others involved from Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø includedÌýAngela Crook, David Dunn,ÌýBecky Turner and Ian White (MRC Clinical Trials Unit at Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø).

WHO consolidated guidelines on tuberculosis: module 3: diagnosis: tests for TB infection.Ìý. The systematic review team was led by Molebogeng (Lele) Rangaka (Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø), and the team included Yohhei Hamada, Lara Goscé, Finna Parkinson and Ting Ting Wang from Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø.

Workshop and resources: Oxford Nanopore sequencing for tuberculosis.Ìý. This workshop took place 22-25th August 2022 at the National Institute for Medical Research (NIMR) at Muhimbili, Dar es Salaam, Tanzania. It was jointly run by Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø and NIMR.ÌýThe aim of the workshop was to provide theoretical and practical training for all of the steps in the tuberculosis Oxford Nanopore Technologies (ONT) sequencing pipeline, from CTAB DNA extraction, DNA quantification best practice, library preparation and setting up a sequencing run, and analysing sequencing data. The workshop was run using a combination of theoretical, laboratory and bioinformatic sessions, with discussion and Q&A sessions throughout the workshop. The website includes links toÌýthe presentations and workshop handbook,Ìýhow to set up a sequencing laboratory (aimed at resource constrained laboratories), how to learn sequencing bioinformatics, andÌýtutorial videos on ONT sequencing.Ìý The Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø team were Linzy Elton and Sylvia Rofael from the Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Centre for Clinical Microbiology.

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