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1. Ïã¸ÛÁùºÏ²ÊÖÐÌØÍøH Biomedical Research Centre

The research of the evidENT team is closely linked to that of the , a partnership between University College London Hospitals NHS Foundation Trust and Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø.Ìý

2. Clinical Trials

MACRO

Defining the best management for adult chronic rhinosinusitis with and without nasal polyps.Ìý

For more information visitÌýthe Ìýor via the .Ìý

Publications:

REGAIN

A first-in-human study of the safety and efficacy of a novel regenerative hearing drug for people with sensorineural hearing loss.

For more information visitÌýthe Ìýor via the

Publications:

SLUMBRS2

Comparing side-lying sleep positioning to back-lying in infants with cleft palate.

For more information visitÌýthe .Ìý

COACH

Comparing cochlear implants with hearing aids in adults with severe hearing loss.

For more information visitÌýthe Ìýor the

FAMOUS

Investigating the clinical and cost effectiveness of a 4-step follow-up and monitoring intervention compared to usual care for adults offered an NHS hearing aid for the first time.

For more information visitÌýthe .Ìý

PLOTS

Comparing topical with oral antibiotics in children with acute otitis media presenting with ear discharge (Netherlands).

For more information visitÌýthe or the

Publications:

OPTIMA

Effectiveness of analgesic ear drops as add-on treatment to oral analgesics in children with acute otitis media (Netherlands).

For more information visitÌýthe .Ìý

3. Data Science Projects

Tele-otology Service

This novel ear and hearing care service tested in North London allows ENT surgeons to assess patients remotely and reduce hospital visits.

For more information visitÌýthe .Ìý

NIHR Health Informatics Collaborative – Hearing Health

Mr Nish Mehta co-leads this collaborative which focuses on making better use of patient hearing health data captured in NHS records. Participating sites across the UK collect hearing data in a standardised and integrated manner and have set up a structure for sharing and analysing these data anonymously. Plans for future research include exploration of effects of known and novel risk factors for hearing loss, identification of genetic causes of hearing loss and identification of candidates for upcoming clinical trials.

For more information visitÌýthe .Ìý

4. Observational Studies

Ototoxicity monitoring in platinum based chemotherapy,

Monitoring ototoxicity in patients undergoing treatment with platinum-based chemotherapy for sarcoma and testicular cancer using tablet based self-administered hearing tests and serum biomarkers.

For more information visitÌýthe .

SeaSHeL

National cohort study investigating patient pathways, quality of life and prognosis for sudden-onset sensorineural hearing loss.

For more information visitÌýthe or the .Ìý

Publications:

COVIDTrach

National cohort study investigating the determinants for the outcome of mechanically ventilated COVID-19 patients undergoing tracheostomy.

For more information visitÌýthe Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø website or the .Ìý

Publications: