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Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Department of Biochemical Engineering

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Meet the Hub team

Meet the members of the Future Targeted Healthcare Manufacturing Hub, based across six leading universities and eight university schools and departments

Logos for EPSRC, Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø, Imperial College London, Loughborough University, University of Manchester, University of Nottingham, University of Warwich

Index

Directors

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Professor Nigel J Titchener-Hooker

Director of Strategy
  • Position: Professor of Biochemical Engineering, Dean of Faculty of Engineering Sciences
  • Expertise: Creation of whole bioprocess models and the use of these to gain process insights and understanding.

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Professor Suzanne Farid

Co-Director: User Engagement and Translation
  • Grand Challenge Lead:
    Digital decisional tools for transforming supply chain management for targeted medicines
  • Position: Professor of Bioprocess Systems Engineering,
    Head of The Department of Biochemical Engineering at Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø
  • Expertise: Bioprocess Decisional Tools, Bioprocess Economics,
    Drug Development Cost Modelling, Capacity planning,
    Portfolio Management, Risk Analysis,
    Multi-Criteria Decision-Making,
    Multi-Objective Simulation & Optimisation,
    Chemometrics

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Professor Paul Dalby

Co-Director: Community Engagement and Training
  • Grand Challenge Lead:
    Digitally-driven manufacturing and analytical platforms for targeted medicines
  • Position: Professor of Biochemical Engineering and Biotechnology,
    Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Biochemical Engineering
  • Expertise: Routes to improve the stability and activity
    of biocatalytic enzymes and therapeutic proteins,
    for ease of manufacture, formulation and delivery to patients

ATMP Manufacturing

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Dr Qasim Rafiq Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Biochemical Engineering 150x300

Co-Investigator
  • Position: Associate Professor in Bioprocessing of Regenerative, Cellular and Gene Therapy
    Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Biochemical Engineering
  • Expertise: Bioprocessing and translation of advanced cell and gene therapies from the lab-scale to clinical and commercial scales
Professor Robert J Thomas

Co-Investigator
  • Position: Professor of Manufacturing for Cell and Gene Therapies
    Loughborough University School of Mechanical, Electrical and Manufacturing Engineering
  • Expertise: Production systems and processes for cell-based products;
    Translation to commercial manufacture and clinical use;
    Automated and scaled production;
    Measurement systems for process control and quality release;
    defining indicators of cell product quality.
Professor Nicolas Szita

Co-Investigator
  • Position: Professor of Bioprocess Microfluidics
    Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Biochemical Engineering
  • Expertise: Translation of bioprocessing concepts into microfluidic systems (or Lab-on-a-chip systems);
    Use of advanced microfabrication techniques for polymers (rapid prototyping), glass and siliconÌý
Dr Nourredine Himoudi

    Researcher
    • Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Biochemical Engineering
    • Training: Master in Biotechnology; PhD in Immunology, research fellow positions in immunotherapy.
      GMP and ATIMPs manufacture management for cancer patients.
    • Expertise: Cancer immunotherapy using viral vectors
      to scale up, validate and manufacture gene-modified T cells
      (TCR and Chimeric Antigen Receptors) for paediatric
      and B cell cancers.
      GMP production management of Gene and Cell Therapy (GCT) /ATIMPs production for cancer patients.

    Cell-Free Synthesis Experimental Research

    ÌýÌý
    Professor Dan Bracewell

    Co-Investigator
    • Position: Professor of Bioprocess Analysis
      Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Biochemical Engineering
    • Expertise: Bioprocess analysis; Speed and capabilities of the analytical techniques used

    Ìý

    Dr Beatrice Melinek

    Researcher
    • Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Biochemical Engineering
    • Training: MEng in Chemical Engineering,
      EngD in Biochemical Engineering
    • Expertise: Cell-free synthesis of biomolecules.
      Additionally, viral vaccine / vector purification and process simulation

    Co-Formulation, Nanoencapsulation and Analytics

    ÌýÌý
    Professor Paul Dalby

    Co-Director: Community Engagement and Training
    • Grand Challenge Lead:
      Digitally-driven manufacturing and analytical platforms for targeted medicines
    • Position: Professor of Biochemical Engineering and Biotechnology,
      Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Biochemical Engineering
    • Expertise: Routes to improve the stability and activity
      of biocatalytic enzymes and therapeutic proteins,
      for ease of manufacture, formulation and delivery to patients
    Professor Jonathan Aylott

    Co-Investigator
    • Position: Professor in Analytical Bioscience
      University of Nottingham School of Pharmacy
    • Expertise: Design, development and implementation of miniaturized analytical devices
    Valentine Anyanwu

    Dr Valentine Anyanwu

    Researcher

    • University of Nottingham
    • Training: PhD in Biochemical Engineering
    • Expertise: Engineering and characterisation of novel formulations
    Dr Raquel Fernandez Garcia

    Researcher
    • University of Nottingham School of Pharmacy
    • Training:ÌýMPharm, PhD
    • Expertise:ÌýEngineering and characterisation of novel formulations
    Braulio Carrillo Sanchez

    Researcher

    • Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Biochemical Engineering
    • Training: PhD in Biochemical Engineering
    • Expertise: cell line development, molecular biology and production of novel modalities such as extracellular vesicles

    Digital Decisional Tools: Datamining, Digital Twins

    ÌýÌý
    Professor Barry Lennox

    Co-Investigator
    • Position: Professor of Applied Control
      University of Manchester
      Department of Electronic and Electrical Engineering
    • Expertise: Robotics for use in Nuclear Engineering Decommissioning
      Leakage and blockage detection in pipelines;
      Multivariate statistical process control;
      Model predictive control;
      Control loop monitoring;
      Monitoring and control of batch processes
    Dr Stephen Goldrick

    Co-Investigator
    • Position: Lecturer in Digital Bioprocess Engineering
      Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Biochemical Engineering
    • Expertise: Advanced Data Analytics, Mathematical Modelling,
      Machine learning, Process Analytical Technology, Digital Twin
    Dr Carlos Duran Villalobos

    Researcher
    • University of Manchester, Department of Electronic and Electrical Engineering
    • Training: Electronics Engineer/ MSc Digital Signal Processing/ PhD Process Control
    • Expertise: Process Control, Multivariate Analysis, Adaptive Control, Data-based Models
      Ìý
    Dr Nivedhitha SwaminathanÌý

    RESEARCHER

    • Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Biochemical Engineering
    • Training: Bachelors Industrial Biotechnology, PhD Bioprocess Engineering
    • Expertise: process analytical technology, mathematical modelling, simulation, process optimization and process control

    Digital Decisional Tools: Supply Chain ManagementÌý

    ÌýÌý
    Professor Suzanne Farid

    CO-DIRECTOR: USER ENGAGEMENT AND TRANSLATION
    • Grand Challenge Lead:
      Digital decisional tools for transforming supply chain management for targeted medicines
    • Position: Professor of Bioprocess Systems Engineering,
      Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Biochemical Engineering
    • Expertise: Bioprocess Decisional Tools, Bioprocess Economics,
      Drug Development Cost Modelling, Capacity planning,
      Portfolio Management, Risk Analysis,
      Multi-Criteria Decision-Making,
      Multi-Objective Simulation & Optimisation,
      Chemometrics
    Professor Nilay Shah

    Co-Investigator
    • Position: Head of Department of Chemical Engineering
      Professor of Process Systems Engineering
      Imperial College London
    • Expertise: Supply chain design and optimisation;
      Process synthesis and development for fine chemicals, pharmaceutical and biochemical processes;
      Mathematical techniques to assess and improve process safetyÌýÌý
    Professor Juergen Branke

    Co-Investigator
    • Position: Professor of Operational Research & Systems
      Warwick Business School, University of Warwick,
    • Expertise: Optimisation under Uncertainty,ÌýMulti-Objective Optimisation, Simulation-based Optimisation
    Dr Maria Papathanasiou

    Co-Investigator
    • Position: Lecturer in Chemical Engineering
    • Imperial College London Chemical Engineering
    • Expertise: Decisional/computational tools, Process modelling/simulation/optimisation, Bioprocess modelling (bioreactors & separation processes)
    Dr Christos Stamatis

    Researcher
    • Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Biochemical Engineering
    • Training: Chemical Engineering (MEng), Biochemical Engineering (MSc, EngD)
    • Expertise: Decisional tools, Process economics for mAbs and bispecifics, Chromatography process developmentÌý
      Ìý
    Dr Andrea Bernardi

    Researcher
    • Imperial College London
      Chemical Engineering
    • Training: Chemical Engineer, PhDÌý
    • Expertise: Computational tools, Model-identification and parameter estimation,
      Process design and optimization, Supply chain optimization, Life cycle assessment
    Dr Siamak Naderi

    Researcher
    • University of Warwick
      Warwick Business School
    • Training: Industrial Engineering (BSc, MSc, Ph.D.)
    • Expertise: Operations and Supply Chain Management,
      Large-Scale Optimisation, Operations Research, Business Analytics

    Reimbursement, Regulatory Strategies and Policy

    ÌýÌý
    Dr Irina Brass

    Dr Irina Brass

    Co-Investigator
    • Position: Associate Professor in Regulation, Innovation and Public Policy,
      Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Science, Technology, Engineering and Public Policy (STEaPP)
    • Expertise: Regulation of emerging technologies;
      managing emerging risks and uncertainty of disruptive innovation;
      public policy and governance
    Dr Manuel Gomes

    CO-INVESTIGATOR, INTERIM

    • Position: Associate Professor of Health Economics Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Department of Applied Health Research
    • Expertise: Development, assessment and translation of statistical methodology in health economics, economic evaluations alongside clinical trials and large observational studies, with particular emphasis on digital and mental health
    Nishma Patel

    Researcher
    • Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Department of Applied Health Research (DAHR)
    • Training: Health Economist
    • Expertise: ÌýEconomic evaluation alongside clinical trials, effects of specialist cancer services, health technology adoption
    Dr Edison Bicudo

    Researcher
    • Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Science Technology, Engineering and Public Policy (STEaPP)
    • Training: PhD, International Politics, Master's in Geography, Bachelor’s Degree in Social Sciences
      Expertise: social and geographical implications of biomedical technologies, e.g. bioinformatics, neuroimaging software, bioprinting
    Hub Logo Holding Image

    Incoming

    Policy Advisor
    • Position: Biomanufacturing Policy Advisor
    • Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Science Technology, Engineering and Public Policy (STEaPP), Policy Impact Unit

    Operations and outreach

    ÌýÌý
    Ìý

    (to be appointed)

    Project Manager
    • Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Biochemical Engineering
    Laura Pasqual Buffone

    Ms Laura Pascual Buffone

    Research Finance Officer
    • Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Biochemical Engineering
      Position:ÌýEPSRC Project Officer and Research Finance Administrator
    Dr Vaughan Thomas

    Dr Vaughan Thomas

    • Outreach Consultant (Industrial)
    Hub Logo Holding Image

    Incoming

    Policy Advisor
    • Position: Biomanufacturing Policy Advisor
    • Ïã¸ÛÁùºÏ²ÊÖÐÌØÍø Science Technology, Engineering and Public Policy (STEaPP), Policy Impact Unit


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